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In one study, some researchers used a CRISPR/Cas9 knockout screen to identify 10 drug-resistant genes, including C1orf115, a previously uncharacterized MDR gene that they named required for drug-induced death 1 (RDD1) (463)

Also, other characteristics of this medication make it potentially dangerous in certain susceptible individuals causing thyroid dysfunction and/or thyroiditis [20, 103]

This trial was conducted et al.-Zahra Hospital, Isfahan, Iran

Br J Pharmacol 176:583593 Teng H, Wu B, Zhao K, Yang G, Wu L, Wang R (2013) Oxygen-sensitive mitochondrial accumulation of cystathionine -synthase mediated by Lon protease