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10.1016/j.biopha.2018.08.136 42 ZhangM.ViennoisE.PrasadM.ZhangY.WangL.ZhangZ.et al (2016)

Compared to the placebo, the tripeptide infusion reduced mean daily food intake by 27%, decreased fat intake, increased protein intake, and enhanced satiety, while not altering food preferences and sweet taste function

Retatrutide is an investigational triple agonist targeting GLP-1, GIP, and glucagon receptors

In addition, exosomes from patients with GD have been found to stimulate the production of proinflammatory cytokines such as IL-1, IL-6, and TNF- (148)