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Selenium and iodine are supported by a relatively robust body of thyroid-specific experimental and clinical studies, whereas evidence for dietary patterns and phytochemicals is more often derived from short-term trials, small cohorts, or non-thyroid populations, as well as secondary syntheses such as reviews and meta-analyses

doi:10.18240/ijo.2018.04.04 15

Regular estrus cycles indicate sexual maturation in rats, primarily associated with the cyclical changes in sex hormones ( Compared to the control group, the hypo group exhibited abnormal follicular development, specifically characterized by an increased number of atretic follicles, and a reduced number of corpora lutea

Grozdanovic M, Laffey KG, Abdelkarim H, Hitchinson B, Harijith A, Moon HG, Park GY, Rousslang LK, Masterson JC, Furuta GT, Tarasova NI, Gaponenko V, Ackerman SJ