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Disclosures: Naoya Tsumura: Nothing to Disclose, Kazuo Imagawa: Nothing to Disclose, Ken Kato: Nothing to Disclose, Osamu Ohara: Nothing to Disclose, Ryuta Nishikomori: Nothing to Disclose, Tatsuki Mizuochi: Nothing to Disclose 2484 DEEP PHENOTYPING OF A NORTH AMERICAN COHORT OF BILE ACID SYNTHETIC DISORDERS Alyssa Kriegermeier 1 Krupa Mysore 2 Estella Alonso 1 Aki Asai 3 Kevin Bove 3 Laura Bull 4 Nathan Goodrich 5 Steve Guthery 6 Sanjiv Harpavat 7 Simon Horslen 8 Evelyn Hsu 9 Karen Jones 10 Binita Kamath 11 Saul Karpen 12 John Magee 13 Jean Molleston 14 Alexander Miethke 15 Philip Rosenthal 4 Ronald Sokol 16 Kenneth Setchell 3 Benjamin Shneider 17 Richard Thompson 18 Pamela Valentino 19 Wen Ye 10 Kathleen Loomes 20 Rohit Kohli 21 , 1 Ann and Robert H

For an optimal result, continue the course for 30 days, give preference to two pill boxes

They reported 100 cases of terminal cancer, independently assessed and refractory to conventional treatment, who lived on average four times longer than 1000 age- and disease-matched controls

Other common side effects include diarrhea, constipation, abdominal pain, vomiting, and decreased appetite