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, 17 Venkatesan T, Levinthal DJ, Tarbell SE, et al

There is no evidence that Depakote ER is useful in the acute treatment of migraine headaches

Overdose may cause profound drowsiness, confusion, ataxia, hypotension, respiratory depression, metabolic acidosis, hyperammonemia, and in severe cases coma

Eventually, a buildup of oxidative stress can cause permanent damage and may lead to things like heart disease and cancer.74 Antioxidants have free electrons that they donate to those oxygen molecules, taming them and allowing the body to repair damage.74 There are thousands of antioxidant compounds, but things like omega-3 fatty acids, vitamins C and E, polyphenols, and carotenoids are potent antioxidants