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doi: 10.1590/0001-3765201720160490 35 DangR.WangM.LiX.WangH.LiuL.WuQ.et al

Additionally, anti-nuclear IgG4 antibody significant titers have been detected in SLE patients, and it has been suggested that the effect of these antibodies on complement consumption and the production of proinflammatory cytokines may play a role in inhibiting the progression of SLE