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In the face of antigen presentation, in an acute, dangerous viral infection, host recovery will be seriously compromised by a lapse, or decrease in Th1 response patterns, including these four IFNy dependent functions: IFNy inhibits replication of ectromelia, vaccinia, and herpes simplex virus- 1 (HSV-1) viruses in mouse macrophages correlated with the cells' production of NO

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Mailloux, Department of Biology, Faculty of Sciences, University of Ottawa, 30 Marie Curie, Ottawa, ON K1N 6N5, Canada e-mail: [email protected] This article was submitted to Molecular Medicine, a section of the journal Frontiers in Cell and Developmental Biology