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As the name implies, biologic therapies are derived from living organisms and consist largely of proteins, sugars, and nucleic acids

Doctors sometimes recommend a very low-calorie diet (under 1,000 calories per day) if someone is obese and has a medical condition, such as high blood pressure, but these diets must be carefully supervised by a doctor

Enhancing ferroptosis requires the inhibition of system Xc, depletion of GSH, and deactivation of GPX4 (Yang et al., 2014)

39 Karyopherin-6 (KPNA6) is a protein which facilitates nuclear import and attenuates Nrf2 signaling, clearance of Nrf2 protein from the nucleus, and restoration of the Nrf2 protein to basal levels