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Cambridge, UK: 2024

P.SafarA.SchutzlerS.MemelinkR.FerrandoA.SpencerH.et al (2011a)

Such phosphorylation leads to the blockade of the tyrosine residues in IRSs, to which the insulin and IGF-1 receptors phosphorylate to activate IRSs and consequently commence the signalling cascade [185, 192], as comprehensively discussed above