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10.1146/annurev-med-041316-085215 31 IbrahimI

[44] Similarly, genetic variations in iron transporter genes known to increase serum iron levels also reduce lifespan and the average number of years spent in good health

Mitochondria in mammalian cells generate most of the cellular energy by means of the oxidative phosphorylation (OXPHOS) that is essential for myriad cellular functions