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It is worth noting that biological females have lower gastric ADH activity than biological males, which is one reason why how BAC differences affect men and women is relevant here the first-pass advantage from food is present in both sexes but slightly stronger in males due to higher enzyme activity

doi:10.1007/s10067-024-06885-9 24

The efficacy and safety of -nicotinamide mononucleotide (NMN) supplementation in healthy middle-aged adults: a randomized, multicenter, double-blind, placebo-controlled, parallel-group, dose-dependent clinical trial