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Gastroenterology 117 , 14271432 (1999)

Although doctors may recommend B12 injection for this purpose when weakness is related to peripheral neuropathy, more research is needed on effectiveness, and Medicare doesnt consider this medically necessary

Vitamin B12 injections offer a range of health benefits and can be particularly advantageous for individuals with B12 deficiency, pernicious anemia, or conditions that impair B12 absorption, such as gastrointestinal disorders (e.g., Crohns disease or celiac disease)

Phase I studies from the late 1980s using IGF-1 to treat Larons Syndrome (GH insensitivity) revealed effective increase in linear growth reaching adult heights using doses ranging from 80 to 240 g/kg/day [264268]