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doi: 10.1007/BF02977716 149 JangSKimYJKimHJLeeJCKimHYKimYCet al

Loss of Von Hippel-Lindau (VHL) tumor suppressor gene function: VHL-HIF pathway and advances in treatments for metastatic renal cell carcinoma (RCC)

Through these two distinct types of interactions, the unliganded L1 domain effectively bridges the two legs of the active IGF1R dimer and brings them into close proximity for receptor activation (Fig

Quantitative real-time PCR (qRT-PCR) analysis of neuroprotective gene expression RNA isolation and quality control The manufacturers protocol was followed to extract total RNA from brain tissue ( n = 6 rodents per group) using Sepasol-RNA I Super G reagent (Cat: 09379-84, Nacalai Tesque, Japan)