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doi: 10.1136/jitc-2021-003725 115 GinefraPHopeHCChiangYHNuttenSBlumSCoukosGet al

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5e,f), indicating that CET had no targeting effect in cells with low EGFR expression

PERK phosphorylates eIF2 to rapidly inhibit general protein translation to reduce the stress load and activate ATF4, which promotes chaperone production and stress response genes [2123]