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In-depth study into the molecular mechanisms underlying ferroptosis and regulators of ferroptosis significantly enhances our understanding of the pathologies of kidney diseases

The lncRNA KMT2E-AS1 can bind to the histone methyltransferase KMT2E, enhance histone H3K4 trimethylation, and drive metabolic reprogramming via HIF-2

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Fatty acid oxidation (FAO), also known as -oxidation, is a metabolic process in which long-chain fatty acids are broken down in the mitochondria to produce acetyl-CoA, which is then utilized for energy production in the tricarboxylic acid (TCA) cycle and electron transport chain [26]