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Many of these climate-related risks worsen with every additional bit of global warmingone of the key motivations behind global efforts to limit that average warming to well below 2C (3.6F)

Percentages of men in the baseline and follow-up samples were, respectively, 46% and 45%, mean age 52.7 and 48.5 years, mean BMI 26.9 kg/m2 and 26.5kg/m2, and prevalences of diabetes 10% and 6.2%

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These shifts in the redox state can modulate key signaling pathways that govern cell fate, such as NOTCH (Neurogenic locus notch homolog protein)