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Peptide calculator (interactive widget) Inputs: Peptide mass in the vial: 5 mg (pre-filled) Reconstitution water volume: slider 15 ml Target dose in the study protocol (mg), typically 0.3 / 0.6 / 1.2 / 2.4 / 4.5 mg according to Lau 2021 and REDEFINE protocols Outputs: Concentration: __ mg/ml Volume per dose: __ ml Visualization of the insulin syringe: __ IU (on a 100 IU scale) Example (REDEFINE 1 CagriSema dose 2.4 mg): 5 mg + 2 ml BAC = 2.5 mg/ml = 2500 g/ml

Applications in Research: Investigations into incretin biology and insulin regulation Preclinical models of obesity and glucose metabolism Studies on energy balance, appetite signaling, and lipid metabolism Research into gut-brain axis and metabolic inflammation Storage & Handling: Store lyophilized Tirzepatide at -20C in a light- and moisture-protected environment

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