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In this case, the HPRB decision notes the patient had a history of deep vein thrombosis, which meant he was already at risk of blood clots

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Although in clinical trials Ipamorelin is often well tolerated and is considered to have a positive safety profile, common side effects of Ipamorelin peptide may include mild irritation or redness at the injection site, headaches, and increased hunger or appetite

Using rectal administration to achieve systemic activity is preferred when the drug is destroyed in the GI tract, if oral administration is not possible because of vomiting, or the patient is unconscious or incapable of swallowing oral formulations