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SKU: 62556374628
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The immunomodulatory effect of the antidepressant sertraline in an experimental autoimmune encephalomyelitis mouse model of multiple sclerosis

Within this FAKSRC complex, SRC phosphorylates FAK at pY861, associating with an increase in SH3-domain-mediated binding of p130Cas to the FAK C-terminal proline-rich regions, which, in turn, promotes cell motility and invasion (Lim et al, 2004)