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Engages GLP-1 receptors in the hypothalamus and hindbrain to reduce hunger, increase satiety, and lower overall energy intake the primary driver of the weight reduction observed in the STEP trial program

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In addition to the abovementioned limitation, the lack of clinical data beyond preclinical trials limits their potential application in clinical settings

[DOI] [PMC free article] [PubMed] [Google Scholar] 44.Irvine N., England-Mason G., Field C.J., Dewey D., Aghajafari F