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Topical GHK-Cu serums are widely available but they deliver a much lower concentration to the dermis than subcutaneous injection because the peptide does not readily cross intact skin

Your iThriveMD provider may recommend it if you're dealing with: Fine lines & loss of firmness For skin that isn't as bouncy as it used to be support for the proteins that keep skin firm Sun damage & photoaging Daily antioxidant defense for skin that sees regular UV and environmental stress Uneven texture & tone Smoother, more even-looking skin without stripping the barrier Post-procedure recovery Gentle support after microneedling, laser, or other in-office treatments Thinning or fragile skin Helps support the structural proteins skin gradually loses with age Sensitive, reactive skin Calming support for skin that flushes or reacts easily to change 15g (1-month) and 45g (3-month) pump bottles Provider-guided peptide skincare protocol How GHK-Cu cream works Three amino acids

In addition, administration of NTG induces migraine-like symptoms in mice, including reduced activity, and facial grimacing behaviors

1 2 "Tolerable Upper Intake Levels For Vitamins And Minerals" (PDF)