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Although brain uptake is modest early on, tracer binding in motor cortex and brainstem increases as disease advances, mirroring human ALS neuroinflammation and expanding diagnostic reach to neuromuscular involvement (142, 146, 147)

Tau-mediated iron export prevents ferroptotic damage after ischemic stroke

In the respiratory tract, microscopic changes were limited to a minimal increase in mucous (goblet) cells in the nasal cavity and carina of male and female rats exposed to the high dose