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If kidney function declines, dose reduction or discontinuation may be necessary

Echocardiography is the main method providers use to diagnose MVP

Primers 341F (5-CCTACGGGGNGGCWGCAG-3) and 806R (5-GGACTACHVGGGGTATCTAAT-3) were selected to amplify the V3-V4 region with an amplification length of 470 bp, to generate amplicons, and for taxonomic analysis