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For example, CuO nanomaterials affect organs such as the kidney, liver, and spleen and can reduce the antioxidant response at the plasma level by enhancing malondialdehyde content

This ultimately leads to the downregulation of various NFB-regulated gene products induced by tumor necrosis factor TNF

GSH is detected in high concentrations in the extracellular epithelial lining fluid of the lower respiratory tract of healthy subjects, and could act as a first-time scavenger of toxic oxygen intermediates and protect against lung cell damage and injury

These sequences are vital to the transcriptional regulation of GATA1/2/3 [48-50]