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Consequently, attempts to block P-gp drug efflux function in the clinic have been discontinued despite the role of P-gp in tumor response to chemotherapeutic drugs [7, 8]

MCF7 cells stably expressing pcDNA3.1(+)-V5_GSTP1 (NH 2 V5-tag), -GSTP1_V5 (COOH V5-tag), -V5_GSTP1_4XCysSer or -V5_GSTP1_4XCysAla/K103R (named MCF7-V5_GSTP1, MCF7-GSTP1_V5, MCF7-V5_GSTP1_4XCysSer, or MCF7-V5_GSTP1-4X_CysAla/Lys103Arg, respectively) were generated as described previously [24], with minor modifications

312,316,317 Notably, the nucleic acid molecules in these conjugates are directly exposed to serum

reported that the use of 2,3-dimercaptopropane-l-sulphonate (DMPS) was beneficial in the treatment of intentional oral poisoning [26]