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doi: 10.1176/appi.ajp.161.2.242 113

Only a small (1015%) induction of autophagy was observed after rapamycin (mTOR inhibitor) treatment in cultured myotubes [60], and rapamycin administration or mTOR knockdown did not induce autophagy in skeletal muscle in vivo [61]

The aim of this narrative review is to outline the processes involved in muscle carnosine metabolism, discuss theoretical and mechanistic modifiable factors which may optimize the muscle carnosine response to BA supplementation, and to make recommendations to guide future research in this area

And while all forms of B12 are generally well-tolerated, clinically, doctors may find cobamamide to be the most well-tolerated of the three bioactive forms