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Despite the different pathways leading to cell death, there is a significant crosstalk between them, which depends on the cellular and tissue context, such as after PD lesion stimuli in animal models (Hartmann et al., 2001

Building upon our extensive proteomics data sets, our initial analysis sought to filter kinases that were repeatedly detected in complex with and/or in proximity to NHR-49

This study marked the first biochemical evidence suggesting that H 2 O 2 produced by colonic epithelial cells is the previously unidentified chemical secreted by colonic epithelial cells leading to the development of UC