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Dysregulation of drugblood protein binding levels would be expected to affect the bioavailability of drugs, depending on the extent of drugprotein binding

In one study involving monozygotic twins and their older brother, a frameshift mutation in KDM5C was identified, inherited from their asymptomatic mother, who exhibited skewed X-inactivation

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Thus, GSTP proteins have multiple functions and are essential for cellular signaling important for various types of cellular events