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In acute and complex cases, treatment is usually surgical

The absorption and metabolism of allicin and its derivatives are not fully understood, but some decomposition likely occurs in the stomach, forming volatile compounds like diallyl sulfide (DAS) and diallyl disulfide (DADS), which further metabolize into compounds such as allyl methyl sulfide (AMS) and allyl mercaptan

Cell-free supernatants were collected and stored at -20C for the future assays and granulomas were harvested by adding ice-cold sterile 1x PBS to wells, followed by gentle scraping to achieve maximum recovery of granuloma lysates and stored at -20C

6.3.2 IREB2 IREB2, an iron-regulatory protein, maintains cellular iron homeostasis by binding to iron-responsive elements and controlling the expression of iron-metabolism genes (202)