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For example, one study found that miR-130b supports the microenvironment required for oocyte development by increasing the survival and proliferation of granulosa and cumulus cells, which in turn improves oocyte maturation [234]

In such cases, healthcare professionals may prescribe methylcobalamin injections to ensure an adequate supply of B12

As we stated in the CY 2025 PFS proposed rule (89 FR 61860), the use of historical benchmarks, when data are available, allow ACOs to know benchmarks prior to start of the performance year and create opportunities for improvement