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DFO, while effective in animal models, exhibits poor bloodbrain barrier (BBB) permeability, necessitating intranasal or intracerebroventricular delivery to achieve therapeutic concentrations (Guo et al., 2013)

The clinical relevance of the metabolism of prostate cancer

This free radical-mediated damage is considered as the initial pathogenic event in degeneration of melanocyte in generalized vitiligo and supplementing glutathione, which is a potent antioxidant, in vitiligo patients may prove to have therapeutic effect

The majority of the existing evidence is derived from preclinical animal models, with limited data available from human studies