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J Mol Neurosci 72(4):679690

It was first isolated and characterized in 1993 by researchers at the University of Zagreb in Croatia, who derived it from a larger protein naturally found in human gastric juice

doi: 10.1289/ehp.10700 81 JiYTianYPanYShengNDaiHFanXet al

Furthermore, melittin inhibits-synuclein post-transcriptional modification, a critical ALS pathogenic pathway, and activates chaperones to prevent protein misfolding