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Influencing factor #2: The tolerability/safety of GLP-1s Why it matters : Even if GLP-1s prove to be highly effective, lack of tolerability or the presence of uncomfortableor even dangerousside effects, could make it difficult for patients to actually take these medications

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While these theoretical and computational studies had been focused on plasticity of excitatory connections between excitatory neurons, their results are not constrained by the transmitter identity of the output of the postsynaptic neuron