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Finally, the random forest model again provided the best predictions for discrimination between complicated appendicitis, and either uncomplicated acute appendicitis or no appendicitis at all, with a joint mean sensitivity of 0.994 0.002 and specificity of 0.129 0.009

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Finally, we detected 39 upregulated lysine acetylation sites of 35 proteins and 169 downregulated lysine acetylation sites of 134 proteins (Supplementary Material 1)