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As opposed to other organisms, for which these conditions would be deleterious, cavefish overcome the environmental challenges and maintain physiological health via metabolic adaptations, potentially contributing to reduced sleep phenotype in cavefish

doi: 10.1016/j.mex.2023.102516 2 AlmaasR.SaugstadO

This deficiency compromises the compensatory antioxidant response to external stimuli, particularly environmental pollutants such as particulate matter, thereby increasing vulnerability to cytotoxic injury (Chan et al