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TF adheres to transferrin receptor 1 (TfR1) on the cell surface, facilitating the internalization of the TFTfR1 complex into endosomes [37]

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We observed the same in our cohort of 70 patients: compared to patient matched healthy tissue, tumors had significantly higher levels of GSSG which they appeared to redox-balance by enhancing GSH production, reflected by a an accumulation of GSH as well as its precursors (Fig

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ALTERATIONS IN GLUTATHIONE PEROXIDASE AND SUPEROXIDE DISMUTASE ACTIVITIES IN PLASMA AND SALIVA IN RELATION TO DISEASE ACTIVITY IN PATIENTS WITH CROHN'S DISEASE INTRODUCTION Crohn's disease (CD) is a chronic inflammatory disorder of the entire gastrointestinal (GI) tract, which most commonly affects the terminal ileum and proximal colon (1-3)

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