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Sarnak MJ, Levey AS, Schoolwerth AC, Coresh J, Culleton B, Hamm LL, et al

doi: 10.1038/gene.2013.22 92 PortelaPJobimLFSalimPHKoffWJWilsonTJJobimMRet al

On the other hand, ANG II signaling via angiotensin II type 1 receptors (AT-1Rs) disrupts both efferocytosis and ECs function as this peptide shifts macrophages from the phagocytic (M2) to proinflammatory (M1) phenotype, a pattern consistent with autoimmune inflammation (Belline et al., 2011)