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More specifically, KEAP1 homodimerizes [124], binds to the ETGE and DLG motifs on Neh2 domain of NRF2, and also acts as a substrate adaptor protein [154] for the KEAP1-NEDD8-CUL3-RBX1 E3 ubiquitin ligase complex [119, 120, 155]

doi: 10.3390/ani10112107 15 KhanMZDariGKhanAYuY

Increased glucose uptake, indicated by augmented glut-1 expression, as well as elevated dependence on glucose metabolism, demonstrated through single-cell SCENITH analysis, were observed in CD8 + T M from COVID(+) patients (Fig