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Description

In support of our findings, upregulation of PPARA signaling has been previously reported to produce oxidative DNA damage and subsequent liver carcinogenesis in several different model systems 74

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Overall, while some TCA cycle products protect neurons, excessive citrate can inhibit glycolysis

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Methylation-dependent loss of RIP3 expression in cancer represses programmed necrosis in response to chemotherapeutics

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It is also present in food, but unfortunately, it is broken down during digestion

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