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Besides direct modulators of iGluR activity, strong candidates for future approaches to treating chronic excitotoxicity include specific inducers of EAAT2 to stimulate L-glu and L-asp uptake, inhibitors of system x to reduce L-glu release as well as compounds that aim to decrease extracellular L-glu by modulating KYN metabolism, e.g., KMO inhibitors

[DOI] [PMC free article] [PubMed] [Google Scholar] 17.Wu D, Chen Q, Chen X, Han F, Chen Z, Wang Y

We were curious to see whether a thermostable GFP (TGP, from coral) 56,57,58 can fulfill this demand

GAC1 is a triterpenoid with a molecular formula of C 30 H 42 O 7 and a molecular weight of 514.6 g/mol