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337 Additionally, navitoclax (also known as ABT-263) is a drug classified as a Bcl-2 family inhibitor. It specifically inhibits the antiapoptotic proteins Bcl-2, Bcl-xL, and Bcl-w within the Bcl family and induces apoptosis through the activation of caspase signaling pathways

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[4] Together, the obesity and diabetes trials give retatrutide the broadest Phase 2 metabolic dataset of the two compounds, and the program has extended into hepatic (liver-fat / MASLD) and cardiometabolic questions that reflect the glucagon arms biology