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All C and D recommendations were the highest grade of evidence of these guidelines, which means recommendations are extracted from case series, single case reports, or poor-quality cohort and casecontrol studies for the C recommendations, and expert opinion without explicit critical appraisal or based on physiology or bench research for the D recommendations

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These are consistent with results from analysis of circulating levels of many of these nutrients in small numbers of dogs with diet-associated DCM in a recent publication that showed no significant differences between diet groups 15

According to the results of the study, when the magnesium serum level reached below the normal level, the probability of migraine headaches increased 35.3 times (189)