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In an experiment using hydrogen peroxide to induce oxidative stress in granulosa cells, EVs derived from granulosa cells contain Nrf2mRNA, an mRNA that can activate antioxidant signaling pathways in other cells, particularly oocytes, thus resisting the oxidative stress environment (Saeed-Zidane et al., 2017)

Su expresin est regulada por las protenas iron-regulatory proteins 1 y 2, altamente expresadas en los tbulos proximales, y que actan como sensores de los niveles de hierro8183

doi: 10.1016/j.jacbts.2020.02.008

Puerarin can ameliorate mitochondrial damage to inhibit cadminum-induced TEC apoptosis in kidney (Song et al., 2016)