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Experimental findings in mouse KD models demonstrate that reduced abundance of specific Clostridium (e.g., Clostridium sensu stricto , Clostridium clusters XIVa ) correlates significantly with vasculitis progression, whereas supplementation with these Clostridium or SCFAs alleviates vascular inflammation by either activating G protein-coupled receptors (GPR43/109A) or inhibiting HDAC activity

Alibay, I., Magarkar, A., Seeliger, D

[DOI] [PMC free article] [PubMed] [Google Scholar] 101.Fu Y., Xu F., Jiang L., Miao Z., Liang X., Yang J., Larsson S.C., Zheng J.-S