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Our recent results demonstrated that EZH2, a methyltransferase for H3K27 dimethylation and trimethylation, was downregulated in the aortic wall of patients with AD compared with the levels in the normal controls [24]

Seeing this work published is very meaningful to me because it represents years of collaborative effort, persistence, and curiosity

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In contrast, in a rat hindlimb ischemia model, TRPV1 activation enhanced endothelial cell proliferation via Ca 2+ dependent transcription factors, including NFAT-1, calsenilin, and MEF2C, thereby promoting positive remodeling of collateral vessels