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2 Boyajian-ONeill LA, McClain RL, Coleman MK, Thomas PP

As Nrf2 is phosphorylated through the protein kinase C pathway, it becomes uncoupled from Keap1, leading to enhanced expression of various anti-inflammatory proteins, antioxidant enzymes, and growth factors

3) entails an increase in the ratio of regressive versus infantile ASD beginning in children born after 1980 [28], which coincides with the time that aspirin use in babies and children was being replaced by APAP use due to increasing awareness of the connection between aspirin and Reye syndrome [29-31]

Compared with conventional LPs, cationic LPs can be transported across the bloodbrain barrier (BBB) via electrostatic interaction with the negative charge of the luminal surface of the BBB, known as adsorptive-mediated transcytosis [19]