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Description

This alludes to the hypothesis that COVID-19-mediated dysfunctional activity and degradation of BMAL1/ARNTL can mediate chronic microglial-inflammatory responses and neuronal ferroptosis-mediated demise

Role of cofactors in protein folding

The in vivo group received intraperitoneal injections of 150 mg/kg disulfiram emulsion 5 days per week, the vehicle group received the emulsion without disulfiram, and the ex vivo group was injected with N91-luc cells that had been pretreated with 100 nM disulfiram for 48 h