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10.3389/fonc.2022.837974 204 SunX.NiuX.ChenR.HeW.ChenD.KangR.et al (2016a)

While we used several markers (including SA--gal, lipofuscin, cyclin-dependent kinase inhibitors, SASP components and transcriptional senescence signatures) to characterize senescence in these models, we have to acknowledge the limitations of our study given the inherent heterogeneity of senescent cells