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(2024) 327:E53343

doi:10.1016/j.clinthera.2024.03.002

The link between inflammation and manifested disease is at present only correlative, and the cause of the inflammatory response can at this point not be determined with certainty

On the other hand, an elevated concentration of homocysteine, and its metabolites such as homocysteine thiolactone and N-homocysteinyllysine result in health problems and has been indicated as an independent risk factor for cardiovascular disease and accelerated atherosclerosis