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As a hydrogenated derivative of berberine, dihydroberberine (DHB) delivers up to 5 greater bioavailability than standard berberine, allowing for enhanced effectiveness at lower doses and improved tolerability.* How It Works: DHB activates AMPK, often referred to as the bodys master metabolic switch. This activation supports insulin sensitivity, promotes healthy cellular glucose uptake, and enhances mitochondrial energy production in muscle and liver tissue.* With a sustained half-life of approximately 46 hours, DHB provides extended metabolic support throughout the day.* Key Benefits: Promotes insulin sensitivity and cellular glucose uptake* Supports healthy lipid metabolism and cholesterol balance* Enhances metabolic flexibility and mitochondrial energy production* More microbiome-friendly than traditional berberine* Supports healthy fasting glucose levels already within the normal range* 2

2011;52 Suppl 2:S1-S62

Upregulation of Growth Factors Research published in the Journal of Peptide Science demonstrates that GHK-Cu stimulates the production of key growth factors including: Vascular Endothelial Growth Factor (VEGF) improves blood vessel formation Nerve Growth Factor (NGF) supports neural repair TGF-1 drives fibroblast activity and wound healing 3